Blar i forfatter "Rathmann, Wolfgang"

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    • Association of glycated hemoglobin A1c levels with cardiovascular outcomes in the general population: results from the BiomarCaRE (Biomarker for Cardiovascular Risk Assessment in Europe) consortium 

      Sinning, Christoph; Makarova, Nataliya; Völzke, Henry; Schnabel, Renate B.; Ojeda, Francisco; Dörr, Marcus; Felix, Stephan B.; Koenig, Wolfgang; Peters, Annette; Rathmann, Wolfgang; Schöttker, Ben; Brenner, Hermann; Veronesi, Giovanni; Cesana, Giancarlo; Brambilla, Paolo; Palosaari, Tarja; Kuulasmaa, Kari; Njølstad, Inger; Mathiesen, Ellisiv B.; Wilsgaard, Tom; Blankenberg, Stefan; Söderberg, Stefan; Ferrario, Marco M.; Thorand, Barbara (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-15)
      Background: Biomarkers may contribute to improved cardiovascular risk estimation. Glycated hemoglobin A<sub>1c</sub> (HbA<sub>1c</sub>) is used to monitor the quality of diabetes treatment. Its strength of association with cardiovascular outcomes in the general population remains uncertain. This study aims to assess the association of HbA<sub>1c</sub> with cardiovascular outcomes in the general ...

    • HbA1c levels in non-diabetic older adults - No J-shaped associations with primary cardiovascular events, cardiovascular and all-cause mortality after adjustment for confoundersin a meta-analysis of individual participant data from six cohort studies 

      Schöttker, Ben; Rathmann, Wolfgang; Herder, Christian; Thorand, Barbara; Wilsgaard, Tom; Njølstad, Inger; Siganos, Galatios; Mathiesen, Ellisiv B.; Saum, Kai-Uwe; Peasey, Anne; Feskens, Edith J.M.; Boffetta, Paolo; Trichopoulou, Antonia; Kuulasmaa, Kari; Kee, Frank; Brenner, Hermann (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-02-11)
      Background:<br>To determine the shape of the associations of HbA1c with mortality and cardiovascular outcomes in non-diabetic individuals and explore potential explanations.<br> Methods:<br> The associations of HbA1c with all-cause mortality, cardiovascular mortality and primary cardiovascular events (myocardial infarction or stroke) were assessed in non-diabetic subjects ≥50 years from six ...

    • Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis 

      Wheeler, Eleanor; Leong, Aaron; Liu, Ching-Ti; Hivert, Marie-France; Strawbridge, Rona J.; Podmore, Clara; Li, Man; Yao, Jie; Sim, Xueling; Hong, Jaeyoung; Chu, Audrey Y.; Zhang, Weihua; Wang, Xu; Chen, Peng; Maruthur, Nisa M.; Porneala, Bianca C.; Sharp, Stephen J.; Jia, Yucheng; Kabagambe, Edmond Kato; Chang, Li-Ching; Chen, Wei-Min; Elks, Cathy E.; Evans, Daniel S.; Fan, Qiao; Giulianini, Franco; Go, Min Jin; Hottenga, Jouke-Jan; Hu, Yao; Jackson, Anne U.; Kanoni, Stavroula; Kim, Young Jin; Kleber, Marcus E.; Ladenvall, Claes; Lecoeur, Cecile; Lim, Sing-Hui; Lu, Yingchang; Mahajan, Anubha; Marzi, Carola; Nalls, Mike A.; Navarro, Pau; Nolte, Ilja M.; Rose, Lynda M.; Rybin, Denis V.; Sanna, Serena; Shi, Yuan; Stram, Daniel O.; Takeuchi, Fumihiko; Tan, Shu Pei; van der Most, Peter J.; Van Vliet-Ostaptchouk, Jana V.; Wong, Andrew; Yengo, Loic; Zhao, Wanting; Goel, Anuj; Martinez Larrad, Maria Teresa; Radke, Dörte; Salo, Perttu; Tanaka, Toshiko; van Iperen, Erik P.A.; Abecasis, Goncalo; Afaq, Saima; Alizadeh, Behrooz Z.; Bertoni, Alain G.; Bonnefond, Amelie; Böttcher, Yvonne; Bottinger, Erwin P.; Campbell, Harry; Carlson, Olga D.; Chen, Chien-Hsiun; Cho, Yoon Shin; Garvey, W. Timothy; Gieger, Christian; Goodarzi, Mark O.; Grallert, Harald; Hamsten, Anders; Hartman, Catharina A.; Herder, Christian; Hsiung, Chao Agnes; Huang, Jie; Igase, Michiya; Isono, Masato; Katsuya, Tomohiro; Khor, Chiea-Chuen; Kiess, Wieland; Kohara, Katsuhiko; Kovacs, Peter; Lee, Juyoung; Lee, Wen-Jane; Lehne, Benjamin; Li, Huaixing; Liu, Jianjun; Lobbens, Stephane; Luan, Jian'an; Lyssenko, Valeriya; Meitinger, Thomas; Miki, Tetsuro; Miljkovic, Iva; Moon, Sanghoon; Mulas, Antonella; Müller, Gabriele; Müller-Nurasyid, Martina; Nagaraja, Ramaiah; Nauck, Matthias; Pankow, James S.; Polasek, Ozren; Prokopenko, Inga; Ramos, Paula S.; Rasmussen-Torvik, Laura; Rathmann, Wolfgang; Rich, Stephen S.; Robertson, Neil R.; Roden, Michael; Roussel, Ronan; Rudan, Igor; Scott, Robert A.; Scott, William R.; Sennblad, Bengt; Siscovick, David S.; Strauch, Konstantin; Sun, Liang; Swertz, Morris; Tajuddin, Salman M.; Taylor, Kent D.; Teo, Yik-Ying; Tham, Yih Chung; Tönjes, Anke; Wareham, Nicholas J.; Willemsen, Gonneke; Wilsgaard, Tom; Hingorani, Aroon D.; Egan, Josephine; Ferrucci, Luigi; Hovingh, G. Kees; Jula, Antti; Kivimäki, Mika; Kumari, Meena; Njølstad, Inger; Palmer, Colin N.A.; Serrano Rios, Manuel; Stumvoll, Michael; Watkins, Hugh; Aung, Tin; Blüher, Matthias; Boehnke, Michael; Boomsma, Dorret I.; Bornstein, Stefan R.; Chambers, John C.; Chasman, Daniel I.; Chen, Yii-Der Ida; Chen, Yduan-Tsong; Cheng, Ching-Yu; Cucca, Francesco; de Geus, Eco J.C.; Deloukas, Panos; Evans, Michele K.; Fornage, Myriam; Friedlander, Yechiel; Froguel, Philippe; Groop, Leif; Gross, Myron D.; Harris, Tamara B.; Hayward, Caroline; Heng, Chew-Kiat; Ingelsson, Erik; Kato, Norihiro; Kim, Bong-Jo; Koh, Woon-Puay; Kooner, Jaspal S.; Korner, Antje; Kuh, Diana; Kuusisto, Johanna; Laakso, Markku; Lin, Xu; Liu, Yongmei; Loos, Ruth J.F.; Magnusson, Patrik K.E.; März, Winfried; McCarthy, Mark I.; Oldehinkel, Albertine J.; Ong, Ken K.; Pedersen, Nancy L.; Pereira, Mark A.; Peters, Annette; Ridker, Paul M.; Sabanayagam, Charumathi; Sale, Michele; Saleheen, Danish; Saltevo, Juha; Schwarz, Peter E.H.; Sheu, Wayne H.-H.; Snieder, Harold; Spector, Timothy D.; Tabara, Yasuharu; Tuomilehto, Jaakko; Van Dam, Rob M.; Wilson, James G; Wilson, James F.; Wolffenbuttel, Bruce H.R.; Wong, Tien Yin; Wu, Jer-Yuarn; Yuan, Jian-Min; Zonderman, Alan B.; Soranzo, Nicole; Guo, Xiuqing; Florez, Jose C.; Sladek, Robert; Dupuis, Josée; Morris, Andrew P.; Tai, E-Shyong; Selvin, Elizabeth; Rotter, Jerome I.; Langenberg, Claudia; Barroso, Inês; Meigs, James B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-12)
      <b>Background:</b> <br> Glycated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and assess glycemic control in patients with diabetes. Previous genome-wide association studies (GWAS) have identified 18 HbA1c-associated genetic variants. These variants proved to be classifiable by their likely biological action as erythrocytic (also associated with erythrocyte traits) or ...

    • Worldwide trends in diabetes since 1980: A pooled analysis of 751 population-based studies with 4.4 million participants 

      Zhou, Bin; Lu, Yuan; Hajifathalian, Kaveh; Bentham, James; Di Cesare, Mariachiara; Danaei, Goodarz; Bixby, Honor; Cowan, Melanie J; Ali, Mohammed K; Taddei, Cristina; Lo, Wei-Cheng; Reis-Santos, Barbara; Stevens, Gretchen A.; Riley, Leanne M.; Miranda, J. Jaime; Bjerregaard, Peter; Rivera, Juan A.; Fouad, Heba M.; Ma, Guansheng; Mbanya, Jean Claude N.; McGarvey, Stephen T.; Mohan, Viswanathan; Onat, Altan; Pilav, Aida; Ramachandran, Ambady; Ben Romdhane, Habiba; Paciorek, Christopher J.; Bennett, James E.; Ezzati, Majid; Abdeen, Ziad A.; Kadir, Khalid Abdul; Abu-Rmeileh, Niveen M.; Acosta-Cazares, Benjamin; Adams, Robert; Aekplakorn, Wichai; Aguilar-Salinas, Carlos A.; Agyemang, Charles; Ahmadvand, Alireza; Al-Othman, Amani Rashed; Alkerwi, Ala'a; Amouyel, Philippe; Amuzu, Antoinette; Bo Andersen, Lars; Anderssen, Sigmund Alfred; Anjana, Ranjit Mohan; Aounallah-Skhiri, Hajer; Aris, Tahir; Arlappa, Nimmathota; Arveiler, Dominique; Assah, Felix K.; Avdicova, Maria; Azizi, Fereidoun; Balakrishna, Nagalla; Bandosz, Piotr; Barbagallo, Carlo M.; Barcelo, Alberto; Batieha, Anwar M.; Baur, Louise A.; Benet, Mikhail; Bernabe-Ortiz, Antonio; Bharadwaj, Sumit; Bhargava, Santosh K.; Bi, Yufang; Bjertness, Espen; Bjertness, Marius Bergsmark; Björkelund, Cecilia; Blokstra, Anneke; Bo, Simona; Boehm, Bernhard O; Boissonnet, Carlos P; Bovet, Pascal; Brajkovich, Imperia; Breckenkamp, Juergen; Brenner, Hermann; Brewster, Lizzy M; Brian, Garry R; Bruno, Graziella; Bugge, Anna; De Leon, Antonio Cabrera; Can, Gunay; Cåndido, Ana Paula C; Capuano, Vincenzo; Carlsson, Axel C; Carvalho, Maria J; Casanueva, Felipe F; Casas, Juan-Pablo; Caserta, Carmelo A; Castetbon, Katia; Chamukuttan, Snehalatha; Chaturvedi, Nishi; Chen, Chien-Jen; Chen, Fangfang; Chen, Shuohua; Cheng, Ching-Yu; Chetrit, Angela; Chiou, Shu-Ti; Cho, Yumi; Chudek, Jerzy; Cifkova, Renata; Claessens, Frank; Concin, Hans; Cooper, Cyrus; Cooper, Rachel; Costanzo, Simona; Cottel, Dominique; Cowell, Chris; Crujeiras, Ana B; D'Arrigo, Graziella; Dallongeville, Jean; Dankner, Rachel; Dauchet, Luc; De Gaetano, Giovanni; De Henauw, Stefaan; Deepa, Mohan; Dehghan, Abbas; Deschamps, Valerie; Dhana, Klodian; Di Castelnuovo, Augusto F; Djalalinia, Shirin; Doua, Kouamelan; Drygas, Wojciech; Du, Yong; Dzerve, Vilnis; Egbagbe, Eruke E; Eggertsen, Robert; El Ati, Jalila; Elosua, Roberto; Erasmus, Rajiv T; Erem, Cihangir; Ergor, Gul; Eriksen, Louise; Escobedo-De La Pena, Jorge; Fall, Caroline H; Farzadfar, Farshad; Felix-Redondo, Francisco J; Ferguson, Trevor S; Fernandez-Berges, Daniel; Ferrari, Marika; Ferreccio, Catterina; Feskens, Edith JM; Finn, Joseph D; Föger, Bernhard; Foo, Leng Huat; Forslund, Ann-Sofie; Francis, Damian K; Do Carmo Franco, Maria; Franco, Oscar H; Frontera, Guillermo; Furusawa, Takuro; Gaciong, Zbigniew; Garnett, Sarah P; Gaspoz, Jean-Michel; Gasull, Magda; Gates, Louise; Geleijnse, Johanna M; Ghasemian, Anoosheh; Ghimire, Anup; Giampaoli, Simona; Gianfagna, Francesco; Giovannelli, Jonathan; Giwercman, Aleksander; Gross, Marcela Gonzalez; Rivas, Juan P Gonzalez; Gorbea, Mariano Bonet; Gottrand, Frederic; Grafnetter, Dusan; Grodzicki, Tomasz; Grøntved, Anders; Gruden, Grabriella; Gu, Dongfeng; Guan, Ong Peng; Guerrero, Ramiro; Guessous, Idris; Guimaraes, Andre L; Gutierrez, Laura; Hambleton, Ian R; Hardy, Rebecca; Kumar, Rachakulla Hari; Hata, Jun; He, Jiang; Heidemann, Christin; Herrala, Sauli; Hihtaniemi, Ilpo Tapani; Ho, Sai Yin; Ho, Suzanne C; Hofman, Albert; Hormiga, Claudia M; Horta, Bernardo L; Houti, Leila; Howitt, Christina; Htay, Thein Thein; Htet, Aung Soe; Htike, Maung Maung Than; Hu, Yang; Hussieni, Abdullatif S; Huybrechts, Inge; Hwalla, Nahla; Iacoviello, Licia; Iannone, Anna G; Ibrahim, M Mohsen; Ikeda, Nayu; Ikram, M Arfan; Irazola, Vilma E; Islam, Muhammad; Iwasaki, Masanori; Jacobs, Jeremy M; Jafar, Tazeen; Jamil, Kazi M; Jasienska, Grazyna; Jiang, Chao Qiang; Jonas, Jost B; Joshi, Pradeep; Kafatos, Anthony; Kalter-Leibovici, Ofra; Kasaeian, Amir; Katz, Joanne; Kaur, Prabhdeep; Kavousi, Maryam; Keinänen-Kiukaanniemi, Sirkka; Kelishadi, Roya; Kengne, Andre P; Kersting, Mathilde; Khader, Yousef Saleh; Khalili, Davood; Khang, Young-Ho; Kiechl, Stefan; Kim, Jeongseon; Kolsteren, Patrick; Korrovits, Paul; Kratzer, Wolfgang; Kromhout, Daan; Kujala, Urho M; Kula, Krzysztof; Kyobutungi, Catherine; Laatikainen, Tiina; Lachat, Carl; Laid, Youcef; Lam, Tai Hing; Landrove, Orlando; Lanska, Vera; Lappas, Georg; Laxmaiah, Avula; Leclercq, Catherine; Lee, Jeannette; Lee, Jeonghee; Lehtimäki, Terho; Lekhraj, Rampal; Leon-Munoz, Luz M; Li, Yanping; Lim, Wei-Yen; Lima-Costa, M Fernanda; Lin, Hsien-Ho; Lin, Xu; Lissner, Lauren; Lorbeer, Roberto; Lozano, Jose Eugenio; Luksiene, Dalia; Lundqvist, Annamari; Lytsy, Per; Machado-Coelho, George LL; Machi, Suka; Maggi, Stefania; Magliano, Dianna J; Makdisse, Marcia; Rao, Kodavanti Mallikharjuna; Manios, Yannis; Manzato, Enzo; Margozzini, Paula; Marques-Vidal, Pedro; Martorell, Reynaldo; Masoodi, Shariq R; Mathiesen, Ellisiv B.; Matsha, Tandi E; McFarlane, Shelly R; McLachlan, Stela; McNulty, Breige A; Mediene-Benchekor, Sounnia; Meirhaeghe, Aline; Menezes, Ana Maria B; Merat, Shahin; Meshram, Indrapal I; Mi, Jie; Miquel, Juan Francisco; Mohamed, Mostafa K; Mohammad, Kazem; Mohammadifard, Noushin; Mohd Yusoff, Muhammad Fadhli; Møller, Niels C; Molnar, Denes; Mondo, Charles K; Morejon, Alain; Moreno, Luis A; Morgan, Karen; Moschonis, George; Mossakowska, Malgorzata; Mostafa, Aya; Mota, Jorge; Motta, Jorge; Mu, Thet Thet; Muiesan, Maria Lorenza; Muller-Nurasyid, Martina; Mursu, Jaakko; Nagel, Gabriele; Namesna, Jana; Nang, Ei Ei K; Nangia, Vinay B; Navarrete-Munoz, Eva Maria; Ndiaye, Ndeye Coumba; Nenko, Ilona; Nervi, Flavio; Nguyen, Nguyen D; Nguyen, Quang Ngoc; Nieto-Martinez, Ramfis E; Ning, Guang; Ninomiya, Toshiharu; Noale, Marianna; Noto, Davide; Al Nsour, Mohannad; Ochoa-Aviles, Angelica M; Oh, Kyungwon; Ordunez, Pedro; Osmond, Clive; Otero, Johanna A; Owusu-Dabo, Ellis; Pahomova, Elena; Palmieri, Luigi; Panda-Jonas, Songhomitra; Panza, Francesco; Parsaeian, Mahboubeh; Peixoto, Sergio Viana; Peltonen, Markku; Peters, Annette; Peykari, Niloofar; Pham, Son Thai; Pitakaka, Freda; Piwonska, Aleksandra; Piwonski, Jerzy; Plans-Rubio, Pedro; Porta, Miquel; Portegies, Marileen LP; Poustchi, Hossein; Pradeepa, Rajendra; Price, Jacqueline F; Punab, Margus; Qasrawi, Radwan F; Qorbani, Mostafa; Radisauskas, Ricardas; Rahman, Mahmudur; Raitakari, Olli; Rao, Sudha Ramachandra; Ramke, Jacqueline; Ramos, Rafel; Rampal, Sanjay; Rathmann, Wolfgang; Redon, Josep; Reganit, Paul Ferdinand M; Rigo, Fernando; Robinson, Sian M; Robitaille, Cynthia; Rodriguez-Artalejo, Fernando; Del CristoRodriguez-Perez, Maria; Rodriguez-Villamizar, Laura A; Rojas-Martinez, Rosalba; Ronkainen, Kimmo; Rosengren, Annika; Rubinstein, Adolfo; Rui, Ornelas; Ruiz-Betancourt, Blanca Sandra; Horimoto, Andrea RV Russo; Rutkowski, Marcin; Sabanayagam, Charumathi; Sachdev, Harshpal S; Saidi, Olfa; Sakarya, Sibel; Salanave, Benoit; Salonen, Jukka T; Salvetti, Massimo; Sanchez-Abanto, Jose; Santos, Diana; Dos Santos, Renata Nunes; Santos, Rute; Saramies, Jouko L; Sardinha, Luis B; Sarrafzadegan, Nizal; Saum, Kai-Uwe; Scazufca, Marcia; Schargrodsky, Herman; Scheidt-Nave, Christa; Sein, Aye Aye; Sharma, Sanjb K; Shaw, Jonathan E; Shibuya, Kenji; Shin, Youchan; Shiri, Rahman; Siantar, Rosalynn; Sibai, Abla M; Simon, Mary; Simons, Judith; Simons, Leon A; Sjostrom, Michael; Slowikowska-Hilczer, Jolanta; Slusarczyk, Przemyslaw; Smeeth, Liam; Snijder, Marieke B; So, Hung-Kwan; Sobngwi, Eugene; Söderberg, Stefan; Solfrizzi, Vincenzo; Sonestedt, Emily; Soumare, Aicha; Staessen, Jan A; Stathopoulou, Maria G; Steene-Johannessen, Jostein; Stehle, Peter; Stein, Aryeh D; Stessman, Jochanan; Stöckl, Doris; Stokwiszewski, Jakub; Stronks, Karien; Strufaldi, Maria Wany; Sun, Chien-An; Sundström, Johan; Sung, Yn-Tz; Suriyawongpaisal, Paibul; Sy, Rody G; Tai, E Shyong; Tamosiunas, Abdonas; Tang, Line; Tarawneh, Mohammed; Tarqui-Mamani, Carolina B; Taylor, Anne; Theobald, Holger; Thijs, Lutgarde; Thuesen, Betina H; Tolonen, Hanna K; Tolstrup, Janne S; Topbas, Murat; Torrent, Maties; Traissac, Pierre; Trinh, Oanh TH; Tulloch-Reid, Marshall K; Tuomainen, Tomi-Pekka; Turley, Maria L; Tzourio, Christophe; Ueda, Peter; Ukoli, Flora AM; Ulmer, Hanno; Uusitalo, Hannu MT; Valdivia, Gonzalo; Valvi, Damaskini; Van Rossem, Lenie; Van Valkengoed, Irene GM; Vanderschueren, Dirk; Vanuzzo, Diego; Vega, Tomas; Velasquez-Melendez, Gustavo; Veronesi, Giovanni; Verschuren, WM Monique; Verstraeten, Roosmarijn; Viet, Lucie; Vioque, Jesus; Virtanen, Jyrki K; Visvikis-Siest, Sophie; Viswanathan, Bharathi; Vollenweider, Peter; Voutilainen, Sari; Vrijheid, Martine; Wade, Alisha N; Wagner, Aline; Walton, Janette; Wan Mohamud, Wan Nazaimoon; Wang, Feng; Wang, Ming-Dong; Wang, Qian; Wang, Ya Xing; Wannamethee, S Goya; Weerasekera, Deepa; Whincup, Peter H; Widhalm, Kurt; Wiecek, Andrzej; Wijga, Alet H; Wilks, Rainford J; Willeit, Johann; Wilsgaard, Tom; Wojtyniak, Bogdan; Wong, Tien Yin; Woo, Jean; Woodward, Mark; Wu, Frederick C; Wu, Shou Ling; Xu, Haiquan; Yan, Weili; Yang, Xiaoguang; Ye, Xingwang; Yoshihara, Akihiro; Younger-Coleman, Novie O; Zambon, Sabina; Zargar, Abdul Hamid; Zdrojewski, Tomasz; Zhao, Wenhua; Zheng, Yingfeng; Cisneros, Julio Zuñiga (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-04-09)
      Background:<br>One of the global targets for non-communicable diseases is to halt, by 2025, the rise in the agestandardised adult prevalence of diabetes at its 2010 levels. We aimed to estimate worldwide trends in diabetes, how likely it is for countries to achieve the global target, and how changes in prevalence, together with population growth and ageing, are aff ecting the number of adults ...